DelveInsight has added a new research study on Carbapenem-Resistant Enterobacteriaceae Infection Market Report with detailed information on the overview, market insights, drugs industry, treatment, growth, size, share, trends, during the forecast period of 2017 to 2030.
Carbapenem-Resistant Enterobacteriaceae Infection Overview
Carbapenems, a class of ß-lactam antibiotics with a broad spectrum of activity, have been the workhorse for treating difficult Gram-negative infections, but with the increasing use of carbapenems in clinical practice, the emergence of Carbapenem-resistant pathogens now poses a great threat to human health.
The Centers for Disease Control and Prevention (CDC) defines Carbapenem-resistant Enterobacteriaceae (CRE) as enterobacteria non-susceptible to any carbapenem or documented to produce carbapenemases. These pathogens have also been described as “nightmare” bacteria by CDC. Also, in 2017, WHO categorized CRE within the critical priority group, against which there is an urgent need to develop new antibiotics.
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Carbapenem-Resistant Enterobacteriaceae Infection Symptoms
Symptoms of a CRE infection vary. They may differ with the type of bacteria involved and the part of the body infected. Some general symptoms of a CRE infection include fever and a rapid pulse. Based on carbapenemase production, CRE is classified into carbapenemase-producing CRE and non- carbapenemase-producing CRE.
Carbapenem-Resistant Enterobacteriaceae Infection Mechanisms
There are three major mechanisms by which Enterobacteriaceae become resistant to carbapenems: enzyme production (carbapenemases), efflux pumps, and porin mutations. Of these, enzyme production is the main resistance mechanism. CP-CRE can produce a large variety of carbapenemases, divided into three groups according to the Ambler classification: Class A, Class B, and Class D ß-lactamases. There is a fourth class, Ambler class C; however, its clinical relevance remains unknown.
Carbapenem-resistant Enterobacteriaceae Infection Diagnosis
It covers the details of conventional and current medical therapies and diagnoses available in the Carbapenem-resistant Enterobacteriaceae Infection market to treat the condition. It also provides country-wise treatment guidelines and algorithms across the United States, Europe, and Japan.
Carbapenem-resistant Enterobacteriaceae Infection Market Report
The DelveInsight Carbapenem-resistant Enterobacteriaceae Infection market report gives a thorough understanding of Carbapenem-resistant Enterobacteriaceae Infection by including disease definition, symptoms, causes, pathophysiology, and diagnosis. It also provides the treatment algorithms and treatment guidelines for Carbapenem-resistant Enterobacteriaceae Infection in the US, Europe, and Japan.
Carbapenem-resistant Enterobacteriaceae Infection Market Growth
In healthcare settings, CRE are transmitted from person to person, often via the hands of healthcare personnel or through contaminated medical equipment. Additionally, sink drains and toilets are increasingly recognized as environmental reservoirs and CRE transmission sources.
Carbapenem-resistant Enterobacteriaceae Infection Market Insights
The scientific community has focused its efforts on identifying new strategies for combating drug resistance by repositioning non-antibiotic drugs in the antimicrobial arsenal or conceptualizing old antibiotics. One of the methodologies in the post-antibiotic era is the use of non-antibiotic drugs for the treatment of multidrug-resistant infections. The benefits are considerable; the details of these drugs’ pharmacokinetics and toxicity are already known, and therefore the drugs can be passed directly into phase 2 of clinical trials. However, the costly disadvantage of clinical trials and patent rights remains.
Carbapenem-resistant Enterobacteriaceae Infection Market Report Scope
Carbapenem-Resistant Enterobacteriaceae Infection Emerging Drugs
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Carbapenem-resistant Enterobacteriaceae Market Report Highlights
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