“The Cystic Fibrosis Market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period (2023-2034). Furthermore, launching various multiple- Cystic Fibrosis pipeline products will significantly revolutionize the Cystic Fibrosis market dynamics”
The Cystic Fibrosis market report provides current treatment practices, Cystic Fibrosis drugs, market share of individual therapies, and current and forecasted 7MM Cystic Fibrosis market size from 2020 to 2034. The report also covers current Cystic Fibrosis treatment market algorithms and unmet medical needs to curate the best opportunities and assess the market’s underlying potential.
Key Takeaways from the Cystic Fibrosis Market Research Report
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Cystic Fibrosis Overview
Cystic fibrosis (CF) is an autosomal recessive condition known as brought on by mutations in the Cystic Fibrosis transmembrane conductance regulator (CFTR) gene. F508del is the most prevalent variation reported globally, but there are over 2000 others, although not all of these are disease-causing.
Cystic Fibrosis Epidemiology Segmentation in the 7MM
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Cystic Fibrosis Drugs Market
The current drugs for CF focus on symptomatic improvement, complication prevention as well as more recently, protein rectifiers to correct underlying structural and functional abnormalities. The paradigm includes inhaled antibiotics for treatment of chronic lung infection, mucolytic for reducing the viscosity of pulmonary mucus, pancreatic enzyme replacement therapy (PERT) for the treatment of CF-associated exocrine pancreatic insufficiency(PPI), and CFTR modulators for enhancing CFTR function, targeting the underlying cause of the disease.
Cystic Fibrosis Market Insights
In condition such as Cystic Fibrosis (CF), close collaboration among all stakeholders is important because collaborative studies and systematic data collection will help further development in the disease management. As a next step, a global prospective study will help all the research fraternity in better understanding of biomarkers and diagnostic tests which will be relevant for future therapeutic clinical trials. In the present scenario a number of agents are being investigated. These molecules are in early, middle and late Phase of their clinical investigation.
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Cystic Fibrosis Companies and Therapies
Cystic Fibrosis Drugs Uptake
ELX-02 (NB-124) is a synthetic aminoglycoside that acts as a ribosome protein modulator. It is a eukaryotic ribosomal selective glycoside (ERSG) that has designed to increase the read-through activity in patients with nonsense mutations which enables the production of sufficient amounts of full-length functional protein to restore activity. The US FDA granted FTD for ELX-02, Eloxx Pharmaceuticals, Inc., drug candidate intended to treat cystic fibrosis patients with nonsense mutations. In addition, the FDA and European Commission granted ELX-02, ODD for the Cystic Fibrosis treatment.
Lonodelestat (previously known as POL6014), is a highly potent and selective peptide inhibitor of human neutrophil elastase (hNE), in development for the treatment of cystic fibrosis and other neutrophilic pulmonary diseases such as non-cystic fibrosis bronchiectasis (NCFB), alpha1 antitrypsin deficiency (AATD) and primary ciliary dyskinesia (PCD). Lonodelestat has ODD for the treatment of CF as well as for AATD and PCD in both EU and US.
LAU-7b (fenretinide) is a novel oral form of fenretinide, an atypical retinoid that acts on certain cell membrane lipids involved in both viral replication and immune-inflammatory responses. Results from a Phase Ib clinical trial in adult patients with CF have shown LAU-7b to have good safety and pharmacokinetic profiles, coupled with promising pharmacodynamics on specific markers of inflammation. Currently, Laurent Pharma has completed two Phase II clinical studies with LAU-7b, a first-in-class pro-resolving drug candidate, in cystic fibrosis and COVID-19.
Learn more about the Cystic Fibrosis Pipeline Therapies in clinical trials @ Cystic Fibrosis Market Landscape
Scope of the Cystic Fibrosis Market Research Report
Discover more about Cystic Fibrosis Drugs in development @ Cystic Fibrosis Ongoing Clinical Trials Analysis
Table of Content
1. Key Insights
2. Cystic Fibrosis Report Introduction
3. Cystic Fibrosis Market Overview at a Glance
4. Cystic Fibrosis Market: Future Perspective
5. Cystic Fibrosis Executive Summary
6. Key Events
7. Cystic Fibrosis Disease Background and Overview
8. Cystic Fibrosis Epidemiology and Patient Population
9. Patient Journey
10. Cystic Fibrosis Marketed Drugs
11. Cystic Fibrosis Emerging Drugs
12. Cystic Fibrosis: Seven Major Market Analysis
13. Key Opinion Leaders’ View
14. Cystic Fibrosis Market Drivers
15. Cystic Fibrosis Market Barriers
16. Cystic Fibrosis SWOT Analysis
17. Cystic Fibrosis Unmet Needs
18. Reimbursement and Cystic Fibrosis Market Access
19. Appendix
20. DelveInsight Capabilities
21. Disclaimer
22. About DelveInsight
About Us
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