DelveInsight’s, “Liver Cirrhosis Pipeline Insight 2025” report provides comprehensive insights about 30+ companies and 30+ pipeline drugs in Liver Cirrhosis pipeline landscape. It covers the Liver Cirrhosis pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Liver Cirrhosis therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Download DelveInsight’s comprehensive Liver Cirrhosis Pipeline Report to explore emerging therapies, key Companies, and future treatment landscapes @ https://www.delveinsight.com/sample-request/liver-cirrhosis-pipeline-insight

Key Takeaways from the Liver Cirrhosis Pipeline Report

• On January 23, 2026- Boehringer Ingelheim conducted a study is to find out the effect of survodutide on MASH and liver fibrosis. The purpose of the second part is to find out how safe and effective survodutide is in improving liver function. Participants are put into 2 groups randomly, which means by chance. 1 group gets survodutide and 1 group gets placebo. Placebo looks like survodutide but does not contain any medicine. Each participant has twice the chance of getting survodutide. Participants and doctors do not know who is in which group. Participants inject survodutide or placebo under their skin once a week. The survodutide doses are slowly increased until the target dose is reached. All participants receive counselling to make changes to their diet and to exercise regularly.
• On January 21, 2026- Ipsen announced a study will have confirmed Primary Biliary Cholangitis (PBC) with inadequate response or intolerance to ursodeoxycholic acid (which is a medication used in the management and treatment of cholestatic liver disease).
• On January 20, 2026- AstraZeneca conducted a study is designed to evaluate the safety of zibotentan/dapagliflozin in combination as compared to zibotentan monotherapy as well as zibotentan/dapagliflozin in combination and zibotentan monotherapy as compared to placebo in patients with cirrhosis with or without a history of decompensation. The study will be conducted in approximately 52 study centers in North America, Asia and Europe.
• DelveInsight’s Liver Cirrhosis pipeline report depicts a robust space with 30+ active players working to develop 30+ pipeline therapies for Liver Cirrhosis treatment.
• The leading Liver Cirrhosis Companies such as Versantis AG, Mirum Pharmaceuticals, Sagimet Biosciences, TenNor Therapeutics, Prism Pharma, Vedanta Biosciences, Lipocine, Gwo Xi Stem Cell Applied Technology, Galectin Therapeutics, Resolution Therapeutics, Ipsen, and AstraZeneca and others.
• Promising Liver Cirrhosis Therapies such as IDN-6556, AZD2389, Resmetirom, GI262570 0.5 mg, Rifaximin SSD 40 mg IR tablet, NRL972, BMS-986263 and others.

Access DelveInsight’s in-depth Liver Cirrhosis Pipeline Analysis for a closer look at promising breakthroughs @ Liver Cirrhosis Clinical Trials and Studies

Liver Cirrhosis Emerging Drugs Profile

• Elafibranor: Ipsen

Elafibranor (GFT-505) is under development for the treatment of colitis, non-alcoholic fatty liver disease, primary biliary cholangitis (PBC), and primary sclerosing cholangitis. The drug candidate is administered orally as a coated tablet. It acts by targeting peroxisome proliferator-activated receptor (PPAR) alpha and PPAR-beta / PPAR- delta. The drug candidate was under development for dyslipidemia, abdominal obesity, type 2 diabetes, Crohn’s disease, insulin resistance and glucose intolerance, colitis and NAFLD/NASH-induced hepatocellular carcinoma (HCC). Currently, the drug is in phase III stage of its clinical trial.

• AZD2389: AstraZeneca

AZD2389 is a hepatoprotectant small molecule developed by AstraZeneca. It is designed to provide protection to the liver. The drug is part of a class aimed at treating liver-related diseases or conditions. Currently, the drug is in Phase II stage of its clinical trial for the treatment of liver Cirrhosis.

• PHIN-214: PharmaIN

PHIN-214 is an investigational drug currently undergoing Phase Ib safety trials by harmaIN, aimed at treating refractory ascites, a condition for which no FDA-approved pharmacological therapy currently exists. Its mechanism of action (MOA) involves targeting and shutting down the Renin-Angiotensin-Aldosterone System (RAAS) signaling pathway, which plays a key role in the retention of excess salt and water by the kidneys. By inhibiting this pathway, PHIN-214 seeks to prevent the accumulation of ascitic fluid, offering potential therapeutic benefits for patients with liver disease who no longer respond to diuretic treatments.

The Liver Cirrhosis pipeline report provides insights into

• The report provides detailed insights about companies that are developing therapies for the treatment of Liver Cirrhosis with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Liver Cirrhosis Treatment.
• Liver Cirrhosis Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Liver Cirrhosis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Liver Cirrhosis market.

Explore DelveInsight’s expert-driven report today! @ Liver Cirrhosis Unmet Needs

Liver Cirrhosis Companies

Versantis AG, Mirum Pharmaceuticals, Sagimet Biosciences, TenNor Therapeutics, Prism Pharma, Vedanta Biosciences, Lipocine, Gwo Xi Stem Cell Applied Technology, Galectin Therapeutics, Resolution Therapeutics, Ipsen, and AstraZeneca and others.

Liver Cirrhosis Pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

• Intra-articular
• Intraocular
• Intrathecal
• Intravenous
• Oral
• Parenteral
• Subcutaneous
• Topical
• Transdermal

Liver Cirrhosis Products have been categorized under various Molecule types such as

• Oligonucleotide
• Peptide
• Small molecule

Download DelveInsight’s latest report to gain strategic insights into upcoming Therapies and key Developments @ Liver Cirrhosis Market Drivers and Barriers, and Future Perspectives

Scope of the Liver Cirrhosis Pipeline Report

• Coverage- Global
• Liver Cirrhosis Companies- Versantis AG, Mirum Pharmaceuticals, Sagimet Biosciences, TenNor Therapeutics, Prism Pharma, Vedanta Biosciences, Lipocine, Gwo Xi Stem Cell Applied Technology, Galectin Therapeutics, Resolution Therapeutics, Ipsen, and AstraZeneca and others.
• Liver Cirrhosis Therapies- IDN-6556, AZD2389, Resmetirom, GI262570 0.5 mg, Rifaximin SSD 40 mg IR tablet, NRL972, BMS-986263 and others.
• Liver Cirrhosis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Liver Cirrhosis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Find out in DelveInsight’s exclusive Liver Cirrhosis Pipeline Report—access it now! @ Liver Cirrhosis Emerging Drugs and Major Companies

Table of Content

1. Introduction
2. Executive Summary
3. Liver Cirrhosis: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Liver Cirrhosis – DelveInsight’s Analytical Perspective
7. Late Stage Products (Phase III)
8. Elafibranor: Ipsen
9. Mid Stage Products (Phase II)
10. Volixibat: Mirum Pharmaceuticals
11. Early Stage Products (Phase I)
12. Mid Stage Products (Phase II)
13. Preclinical Stage Products
14. PVT201: Parvus Therapeutics
15. Inactive Products
16. Liver Cirrhosis – Collaborations Assessment- Licensing / Partnering / Funding
17. Liver Cirrhosis – Unmet Needs
18. Liver Cirrhosis – Market Drivers and Barriers
19. Appendix

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