DelveInsight’s Spinal Cord Injury pipeline report comprehensive insights into 40+ companies and 40+ pipeline drugs in the Spinal Cord Injury pipeline landscape. It also includes clinical and nonclinical stage products in the pipeline drug profiles. It also assesses therapeutics based on product type, stage, route of administration, and molecule type.
Some of the Key Highlights from the Spinal Cord Injury Pipeline Report
There are currently 40+ drugs in the pipeline for Spinal Cord Injury treatment.
The Spinal Cord Injury pipeline comprises therapies that are in different stages of the clinical phase include KP-100IT, ES 135, PMZ-1620, MT 3921, AST-OPC1, FAB117-HC, NEU-2000, ALMB0166, KAND 567, Allogeneic stem cell therapy, and others and are expected to be available for Spinal Cord Injury treatment soon.
Key pharmaceutical players which are evaluating their drug candidates for Spinal Cord Injury treatment include Kringle Pharma, Eusol Biotech, Pharmazz, Mitsubishi Tanabe Pharma, Lineage Cell Therapeutics, Histocell, AmKor Pharma, AlaMab therapeutics, Kancera, Athersys, among others.
In September 2019, the Japanese Ministry of Health, Labour, and Welfare designated HGF (KP-100IT) as an orphan drug for acute spinal cord injury.
GTX Medical and NeuroRecovery Technologies announced their merger in October 2019 to form a leading global company dedicated to developing novel neuromodulation therapies to improve the functional recovery of people with Spinal Cord Injuries (SCI).
Allogeneic stem cell therapy is being developed and investigated in preclinical studies by Athersys for Spinal Cord Injury treatment.
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Spinal Cord Injury: Overview
Traumatic damage to the spinal cord or nerves at the end of the spinal canal is referred to as spinal cord injury. This has an impact on the transmission of sensory and motor signals across the lesion site. Spinal cord injury is a debilitating neurological condition that has a significant socioeconomic impact on both affected individuals and the healthcare system. There are two types of spinal cord injuries: incomplete and complete injury.
Spinal Cord Injury Diagnosis
The goal of diagnosis is to determine the extent of neurological injury, the degree of residual sensory and motor function, and any complications. Imaging technology is an important part of the chronic spinal cord injury diagnostic process. MRI scans are the gold standard for imaging neurological tissues like the spinal cord, ligaments, discs, and soft tissues.
Spinal Cord Injury Treatment
Individuals suffering from Spinal Cord Injuries or disorders require multidisciplinary care management in order to achieve the best possible health outcomes. Chronic Spinal Cord Injury treatments aim to avoid or improve pathophysiological mechanisms such as glial scar formation, demyelination, and astrogliosis.
Spinal Cord Injury Pipeline Analysis: Drug Profiles
KP-100IT: Kringle Pharma
Product Description
HGF (KP-100IT) protects neurons and stimulates axon elongation, therefore it could be used as a Spinal Cord Injury treatment. Currently, it is being developed and investigated in Phase III clinical trials for Spinal Cord Injury by Kringle Pharma.
Phase III
NCT04475224: Kringle Pharma began a non-randomized, multicenter, and confirmatory study of KP-100IT intrathecal administration in subjects with acute spinal cord injury in July 2020. This is a non-randomized, multicenter, confirmatory trial in people with acute spinal cord injuries using intrathecal administration of KP-100IT, a code for HGF (Hepatocyte Growth Factor) formulation for intrathecal injection.
For more information on the emerging drugs and companies, visit Spinal Cord Injury Clinical Trials
Spinal Cord Injury Pipeline Therapies and Key Companies
ES 135: Eusol Biotech
PMZ-1620: Pharmazz
MT 3921: Mitsubishi Tanabe Pharma
AST-OPC1: Lineage Cell Therapeutics
FAB117-HC: Histocell
NEU-2000: AmKor Pharma
ALMB0166: AlaMab therapeutics
KAND 567: Kancera
Allogeneic stem cell therapy: Athersys
Spinal Cord Injury Therapeutics Assessment
By Product Type
Monotherapy
Combination Therapy
By Stage
Discovery
Pre-Clinical
Phase I
Phase II
Pre-registration
By Route of Administration
Inhalation
Intravenous
Oral
Subcutaneous
By Molecule Type
Small Molecule
Stem Cell Therapy
Gene Therapy
Targets
Immune System
Multiple Kinase
By Mechanism of Action
Protease Inhibitors
Immunomodulatory
Scope of the Report
Coverage: Global
Spinal Cord Injury Key Players: Kringle Pharma, Eusol Biotech, Pharmazz, Mitsubishi Tanabe Pharma, Lineage Cell Therapeutics, Histocell, AmKor Pharma, AlaMab therapeutics, Kancera, Athersys,among others
Spinal Cord Injury Pipeline Therapies: KP-100IT, ES 135, PMZ-1620, MT 3921, AST-OPC1, FAB117-HC, NEU-2000, ALMB0166, KAND 567, Allogeneic stem cell therapy, and others
Table of Contents
1.
Introduction
2.
Executive Summary
3.
4.
Spinal Cord Injury- Analytical Perspective In-depth Commercial Assessment
5.
Spinal Cord Injury Pipeline Therapeutics
6.
Spinal Cord Injury Late Stage Products (Phase III)
7.
Spinal Cord Injury Mid Stage Products (Phase II)
8.
Spinal Cord Injury Early Stage Products (Phase I/II)
9.
Spinal Cord Injury Early Stage Products (Phase I)
10.
Spinal Cord Injury Pre-clinical and Discovery Stage Products
11.
12.
Spinal Cord Injury Inactive Products
13.
Spinal Cord Injury Company-University Collaborations (Licensing/Partnering) Analysis
14.
Spinal Cord Injury Key Companies
15.
Spinal Cord Injury Key Products
16.
Spinal Cord Injury- Unmet Needs
17.
Spinal Cord Injury- Market Drivers and Barriers
18.
Spinal Cord Injury- Future Perspectives and Conclusion
19.
Spinal Cord Injury Analyst Views
20.
Appendix
21.
About DelveInsight
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Key questions answered in the Spinal Cord Injury Pipeline Report
What are the treatment options for Spinal Cord injury?
How many pharmaceutical companies are working on cures for Spinal Cord injury?
Which of these firms’ pharmaceuticals is the most widely used?
How many Spinal Cord injury medications does each company make in total?
How many drugs in the Spinal Cord injury pipeline are in the early, middle, or late phases of development?
How many of the in-development therapies can be used alone or in combination with other treatments?
What are the most important industry-industry and industry-academy collaborations, mergers and acquisitions, and licensing practices that affect Spinal Cord injury?
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