DelveInsight’s “Small Cell Lung Cancer Market Insights, Epidemiology and Market Forecast – 2034” report delivers an in-depth understanding of the Small Cell Lung Cancer, historical and forecasted epidemiology as well as the Small Cell Lung Cancer market trends in the United States, EU4 (Germany, France, Italy, Spain) and the United Kingdom, and Japan.

 

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Key Takeaways from the Small Cell Lung Cancer Market Report

• In January 2025:- Hoffmann-La Roche:- The purpose of this multicenter study in China is to evaluate the safety and efficacy of tiragolumab plus atezolizumab and carboplatin and etoposide (CE) compared with placebo plus atezolizumab and CE in participants with untreated extensive-stage small cell lung cancer.
• In January 2025:- AstraZeneca:- This is a Phase I/II study designed to evaluate if experimental anti-TIGIT/anti-PD-1 bispecific antibody rilvegostomig (AZD2936) is safe, tolerable and efficacious in participants with Advanced or Metastatic Non-small Cell Lung Cancer.
• In January 2025:- Boehringer Ingelheim:- The purpose of this study is to find a suitable dose of BI 764532 that people with advanced cancer can tolerate when taken alone. 2 different doses of BI 764532 are tested in this study. Another purpose is to check whether BI 764532 can make tumours shrink. BI 764532 is an antibody-like molecule (DLL3/CD3 bispecific) that may help the immune system fight cancer.
• It is estimated that for lung cancer in the US in 2023 are about 238,340 new cases of lung cancer (117,550 in men and 120,790 in women). The society also reported that most lung cancer statistics include both small cell lung cancer and non-small cell lung cancer. About 10% to 15% of all lung cancers are Small Cell Lung Cancer and about 80% to 85% are Non–Small Cell Lung Cancer.
• In the United States, Small Cell Lung Cancer is slightly less common in men (13%) compared to women (14%). The risk of lung cancer increases with age. Both men and women are most likely to be diagnosed with Small Cell Lung Cancer between the ages of 75 and 79.
• In the UK around 15 to 20 out of every 100 lung cancers (around 15 to 20%) diagnosed are this type. It is usually caused by smoking. These cancers tend to spread quite early on.
• It has been observed that about three-quarters of Small Cell Lung Cancer patients are diagnosed with extensive-stage Small Cell Lung Cancer.
• Among the EU4 and the UK, Germany had the highest incident population of Small Cell Lung Cancer, followed by the United Kingdom and France. On the other hand, Spain had the lowest incidence of cases of Small Cell Lung Cancer in 2022.
• The leading Small Cell Lung Cancer Companies such as Bristol-Myers Squibb, Merck, AstraZeneca, PharmaMar, EpicentRx, and others.
• Promising Small Cell Lung Cancer Therapies such as Atezolizumab Injection, Amivantamab, Lazertinib, Pemetrexed 500 mg, AL8326 tablets, and others.

 

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Small Cell Lung Cancer Epidemiology Segmentation in the 7MM

• Total Small Cell Lung Cancer Incident cases
• Small Cell Lung Cancer gender-specific incident cases
• Small Cell Lung Cancer age-specific incident cases
• Small Cell Lung Cancer Line-wise treated cases

 

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Marketed Small Cell Lung Cancer Drugs

• ZEPZELCA (lurbinectedin): PharmaMar and Jazz Pharmaceuticals

In June 2020, the US Food and Drug Administration granted accelerated approval to ZEPZELCA (lurbinectedin) for adult patients with metastatic Small Cell Lung Cancer with disease progression on or after platinum-based chemotherapy. ZEPZELCA, also known as PM1183, is an alkylating drug that binds guanine residues within DNA. This triggers a cascade of events that can affect the activity of DNA binding proteins, including some transcription factors, and DNA repair pathways, resulting in disruption of the cell cycle and eventual cell death. ZEPZELCA is the first new drug approved for second-line treatment since 1996. ZEPZELCA offers several benefits over the standard therapy, HYMCAMTIN, with one notable advantage being a shorter treatment window. When administering ZEPZELCA intravenously, the process lasts for a mere hour, occurring once every three weeks. Conversely, the older therapy necessitates a more time-consuming regimen, requiring a five-day intravenous course of treatment every three weeks.

 

• IMFINZI (durvalumab): AstraZeneca

In March 2020, the US Food and Drug Administration approved IMFINZI (durvalumab), in combination with etoposide and either carboplatin or cisplatin as the first-line treatment of patients with extensive-stage Small Cell Lung Cancer. IMFINZI is a human monoclonal antibody that binds to PD-L1 and blocks the interaction of PD-L1 with PD-1 and CD80, countering the tumor’s immune-evading tactics and releasing the inhibition of immune responses.

 

Emerging Small Cell Lung Cancer Drugs

• RRx-001: EpicentRx

RRx-001, which is being investigated by EpicentRx, is a highly selective NLRP3 inhibitor under investigation in a Phase III trial for the treatment of Small Cell Lung Cancer. Currently, the 3L+ Small Cell Lung Cancer REPLATINUM Phase III study is enrolling patients in the US and China. RRx-001, a tumor-activated small molecule that inhibits the NLRP3 inflammasome and repolarizes tumor-associated macrophages (TAMs), is used to restore sensitivity to chemotherapy that has already been tried.

 

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Small Cell Lung Cancer Drugs Market Landscape

Immunotherapies, including immune checkpoint inhibitors (ICIs), have revolutionized the treatment of various cancers and have emerged as a topic of immense interest in the case of Small Cell Lung Cancer (Small Cell Lung Cancer). Notably, recent advancements have shown improved survival rates in extensive-stage Small Cell Lung Cancer through the incorporation of anti-programmed death ligand 1 (PD-L1) inhibitors alongside platinum-based chemotherapy as the primary treatment. Consequently, the combination of chemoimmunotherapy has now gained official approval as the standard of care.

 

Small Cell Lung Cancer Market Outlook

For the last three decades, there has been minimal progress in enhancing the survival rates of patients afflicted with Small Cell Lung Cancer. Unfortunately, the clinical outcomes for these patients continue to be unfavorable primarily due to the disease’s rapid cell division, propensity for early and extensive metastasis, and the development of resistance to chemotherapy. There are a number of treatment options for Small Cell Lung Cancer. These treatment options are used to treat a specific patient’s lung cancer that depends on the stage of cancer, the patient’s overall health, including how well the organs of the patient’s body are functioning, and the patient’s preferences. Surgery, chemotherapy, radiation therapy, and immunotherapy are approved and mainly used treatment choices.

 

Small Cell Lung Cancer Treatment Market

The choice of treatment option is dependent on the stage of Small Cell Lung Cancer, symptoms, age, how fast it is growing, and whether patients may suffer various patterns of recurrence requiring subsequent lines of rescue therapies. The most commonly used chemotherapy regimen is Etoposide or Irinotecan plus a platinum-based drug such as Cisplatin or Carboplatin. For people with limited-stage Small Cell Lung Cancer, chemotherapy plus radiation therapy to the chest is given daily over several weeks. People with extensive-stage cancer initially receive chemotherapy for 3 to 4 months or they may receive chemotherapy in combination with immunotherapy.

 

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Scope of the Small Cell Lung Cancer Market Report

• Coverage- 7MM
• Study Period- 2020-2034
• Small Cell Lung Cancer Companies- Bristol-Myers Squibb, Merck, AstraZeneca, PharmaMar, EpicentRx, and others.
• Small Cell Lung Cancer Therapies- Atezolizumab Injection, Amivantamab, Lazertinib, Pemetrexed 500 mg, AL8326 tablets, and others.
• Small Cell Lung Cancer Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
• Small Cell Lung Cancer Unmet Needs, KOL’s views, Analyst’s views, Small Cell Lung Cancer Market Access and Reimbursement

 

Table of Content

1. Key Insights

2. Report Introduction

3. Executive Summary

4. Key Events

5. Epidemiology and Market Forecast Methodology

6. Small-cell Lung Cancer Market Overview at a Glance

7. Small Cell Lung cancer (SCLC): Disease Background and Overview

8. Small Cell Lung Cancer Epidemiology and Patient Population: 7MM

9. Current Treatment Practices for Small-cell Lung Cancer (Small-cell Lung Cancer)

10. Small Cell Lung Cancer Patient Journey

11. Key Endpoints in Small-cell Lung Cancer Clinical Trials

12. Marketed Small Cell Lung Cancer Products

List to be continued……

13. Emerging Small Cell Lung Cancer Therapies

14. Small Cell Lung cancer Market: Seven Major Market Analyses

15. Small Cell Lung Cancer Unmet Needs

16. Small Cell Lung Cancer SWOT Analysis

17. Small Cell Lung Cancer KOL Views

18. Small Cell Lung Cancer Market Access and Reimbursement Scenario

19. Appendix

20. DelveInsight Capabilities

21. Disclaimer

22. About DelveInsight

 

About Us

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