“TRK Fusion Cancer Epidemiology” report has been added to DelveInsight
Overview of TRK Fusion Cancer epidemiology, pathophysiology, various diagnostic approaches, and treatment algorithm, including detailed chapters for marketed products and emerging therapies
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TRK Fusion Cancer Overview
Tropomyosin receptor kinase (TRK) is family of three neurotrophic receptor tyrosine kinase proteins (TRKA, TRKB, and TRKC) encoded by the NTRK1, NTRK2, and NTRK3 genes located on chromosomes 1q23.1, 9q21.33, and 15q25.3, respectively.
TRK Fusion Cancer: Geography Covered
TRK Fusion Cancer Epidemiology Insights
TRK fusion cancer is a term given to cancers with neurotrophic receptor tyrosine kinase (NTRK) gene fusion. These fusion genes encodes for TRK fusion proteins that activates various signaling pathways which are essential for tumor growth and survival. NTRK gene fusion is identified in around 25 different cancers.
Important facts of TRK Fusion Cancer report
TRK Fusion Cancer Epidemiology Segmentation
TRK Fusion Cancer Epidemiology Report
These receptors are typically expressed in neuronal tissues and have a high affinity for and are activated by neurotrophins. Single-pass transmembrane receptor tyrosine kinases, high-affinity nerve growth factor receptor (TRKA), BDNF/NT-3 growth factor receptor (TRKB), and NT-3 growth factor receptor (TRKC) are essential for the development, maintenance, and function of neural tissues.
TRK Fusion Cancer Diagnosis
The diagnosis of this gene fusion can be identified by various approaches, including fluorescent in situ hybridization, reverse transcription-polymerase chain reaction, immunohistochemistry, next-generation sequencing, and ribonucleic acid-based multiplexed assays.
TRK Fusion Cancer Report Highlights
Following is the TOC of TRK Fusion Cancer report
1. Key Insights
2. Executive Summary of TRK Fusion Cancer
3. TRK Fusion Cancer: Disease Background and Overview
4. Patient Journey
5. Epidemiology and Patient Population
6. Treatment Algorithm, Current Treatment, and Medical Practices
7. KOL Views
8. Unmet Needs
9. Appendix
10. DelveInsight Capabilities
11. Disclaimer
12. About DelveInsight
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